Benzodiazepines - side effects and toxicity
Typically, side effects include daily sedation, dizziness, impaired coordination of movements, ataxia (imbalance), fatigue, increased reaction time, impaired mental and psychomotor function, impaired thinking, confusion, and short-term amnesia. Blurred vision, hypotension, slurred speech, tremor, urinary incontinence, constipation, rash, dry mouth, nausea and vomiting are also possible.
In some cases, benzodiazepines can also cause paradoxical reactions such as aggression, increased irritability, anxiety, insomnia, hyperactivity, nightmares and restless sleep, paranoia, suicidal thoughts, depression. These manifestations are very rare, but they do happen. Benzodiazepines can detect previously latent depression.
Although rare, respiratory depression, apnea, and cardiac arrest may occur in adults and seriously ill patients with limited respiratory reserve, mainly with intravenous administration of benzodiazepines. They can suppress breathing in patients with undiagnosed sleep apnea or chronic lung disease.
With prolonged use of benzodiazepines, tolerance, physical and mental dependence may develop. Tolerance to their sedative, hypnotic, and anticonvulsant effects develops, while tolerance to their anxiolytic effects is extremely rare. Benzodiazepines cross the placental barrier and can cause withdrawal symptoms in newborns from mothers who took benzodiazepines 2-3 months before birth./
Toxicity
Physical and mental dependence on benzodiazepines increases with increasing dose and duration of treatment. The risk is higher in patients with a history of alcohol and drug abuse. With developed physical dependence, withdrawal reactions may occur upon abrupt discontinuation of the drug. Instead, it is recommended to gradually reduce the dose over a period of 10-14 days.
Patients with a history of seizures who are addicted to long-acting benzodiazepines should be hospitalized and the dose gradually reduced (sometimes for more than 20 days). Overdose can lead to respiratory depression and death. Treatment and withdrawal of benzodiazepines should be carried out under strict medical supervision. Le code promo 1xbet est la garantie de bénéficier de la meilleure offre de bienvenue. En l'appliquant, vous activez un bonus de 100% sur votre premier dépôt, pour un maximum de 130 €. Cette manne financière vous offre une marge de manœuvre exceptionnelle pour découvrir toutes les fonctionnalités du site, des paris en direct aux jackpots progressifs, en toute sérénité.
